Gold(I)/Zn(II) catalyzed tandem hydroamination/annulation reaction of 4-yne-nitriles.
نویسندگان
چکیده
The tandem hydroamination-annulation reaction of 4-pentyne-nitriles in the presence of amine nucleophiles and a cooperatively operating catalyst system, consisting of Ph(3)PAuCl and Zn(ClO(4))(2), provides an efficient route to 2-aminopyrroles. Two regioisomeric 2-aminopyrroles were formed in moderate to good yields.
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ورودعنوان ژورنال:
- Chemical communications
دوره 46 42 شماره
صفحات -
تاریخ انتشار 2010